Published Papers



[50] Gelman, J. S.; Sironi, J.; Dasqupta, S.; Castro, L. M.; GOZZO, F. C.; Ferro, E. S.; Fricker, L. D. Alterations of the intracellular peptidome in response to the proteasome inhibitor bortezomib. PLOS One 2013, 8, e53263. DOI: 10.1371/journal.pone.0053263

[49] Barbosa, H. D.; Souza, D. L. Q.; KOOLEN, H. H. F.; GOZZO, F. C.; Arruda, M. A. Z. Sample preparation focusing on plant proteomics: extraction, evaluation and identification of proteins from sunflower seeds. Analytical Methods 2013, 5, 116-123. DOI: 10.1039/C2AY25503K


[48] Apparicio, M.; Ferreira, C. R.; Tata, A.; Santos, V. G.; Alves, A. E.; Mostachio, G. Q.; Pires-Butler, E. A.; Motheo, T. F.; Padilha, L. C.; PILAU, E. J.; GOZZO, F. C.; Eberlin, M. N.; Lo Turco, E. G.; Luvoni, G. C.; Vicente, W. R. R. Chemical Composition of Lipids Present in Cat and Dog Oocyte by Matrix-Assisted Desorption Ionization Mass Spectrometry (MALDI- MS). Reproduction in Domestic Animals 2012, 47, 113-117. DOI: 10.1111/rda.12003

[47] Ramos, L. M.; Tobio, A. Y. P. D. Y.; Santos, M. R.; Oliveira, H. C. B.; GOMES, A. F.; GOZZO, F. C.; Oliveira, A. L.; Neto, B. A. D. Mechanistic Studies on Lewis Acid Catalyzed Biginelli Reactions in Ionic Liquids: Evidence for the Reactive Intermediates and the Role of the Reagents. Journal of Organic Chemistry 2012, 77, 10184-10193. DOI: 10.1021/jo301806n

[46] Montani, D. A.; Cordeiro, F. B.; Regiani, T.; Victorino, A. B.; PILAU, E. J.; GOZZO, F. C.; Ferreira, C. R.; Fraietta, R.; Lo Turco, E. G. The follicular microenviroment as a predictor of pregnancy: MALDI-TOF MS lipid profile in cumulus cells. Journal of Assisted Reproduction and Genetics 2012, 29, 1289-1297. DOI: 10.1007/s10815-012-9859-y

[45] Fariello, R. M.; Pariz, J. R.; Spaine, D. M.; GOZZO, F. C.; PILAU, E. J.; Fraietta, R.; Bertolla, R. P.; Andreoni, C.; Cedenho, A. P. Effect of smoking on the functional aspects of sperm and seminal plasma protein profiles in patients with varicocele. Human Reproduction 2012, 27, 3140-3149. DOI: 10.1093/humrep/des287

[44] Russo, L. C.; Castro, L. M.; GOZZO, F. C.; Ferro, E. S. Inhibition of thimet oligopeptidase by siRNA alters specific intracellular peptides and potentiates isoproterenol signal transduction. FEBS Letters 2012, 586, 3287-3292. DOI: 10.1016/j.febslet.2012.07.002

[43] Russo, L. C.; Asega, A. F.; Castro, L. M.; Negraes, P. D.; Cruz, L.; GOZZO, F. C.; Ulrich, H.; Camargo, A. C. M.; Rioli, V.; Ferro, E. S. Natural intracellular peptides can modulate the interactions of mouse brain proteins and thimet oligopeptidase with 14-3-3e and calmodulin. Proteomics 2012, 12, 2641-2655. DOI: 10.1002/pmic.201200032

[42] Berti, D. A.; Russo, L. C.; Castro, L. M.; Cruz, L.; GOZZO, F. C.; Heimann, J. C.; Lima, F. B.; Oliveira, A. C.; Andreotti, S.; Prada, P. O.; Heimann, A. S.; Ferro, E. S. Identification of intracellular peptides in rat adipose tissue: Insights into insulin resistance. Proteomics 2012, 12, 2668-2681. DOI: 10.1002/pmic.201200051

[41] FIORAMONTE, M.; Santos, A. M.; McIlwain, S.; Noble, W. S.; Franchini, K. G.; GOZZO, F. C. Analysis of secondary structure in proteins by chemical cross-linking coupled to MS. Proteomics 2012, 12, 2746-2752. DOI: 10.1002/pmic.201200040

[40] Toledo, T. T.; Nogueira, S. B.; Cordenunsi, B. R.; GOZZO, F. C.; PILAU, E. J.; Lajolo, F. M.; Nascimento, J. R. O. Proteomic analysis of banana fruit reveals proteins that are differentially accumulated during ripening. Postharvest Biology and Technology 2012, 70, 51-58. DOI: 10.1016/j.postharvbio.2012.04.005

[39] Souza, C. E. A.; Rego, J. P. A.; Lobo, C. H.; Oliveira, J. T. A.; Nogueira, F. C. S.; Domont, G. B.; FIORAMONTE, M.; GOZZO, F. C.; Moreno, F. B.; Monteiro-Moreira, A. C. O.; Figueiredo, J. R.; Moura, A. A. Proteomic analysis of the reproductive tract fluids from tropically-adapted Santa Ines rams. Journal of Proteomics 2012, 14, 4436-4456. DOI: 10.1016/j.jprot.2012.05.039

[38] Malvezzi, A.; Higa, P. M.; Amaral, A. T. D.; Silva, G. M.; GOZZO, F. C.; Ferro, E. S.; Castro, L. M.; Rezende, L.; Monteiro, G.; Demasi, M. The Cysteine-Rich Protein Thimet Oligopeptidase as a Model of the Structural Requirements for S-glutathiolation and Oxidative Oligomerization. PLOS One 2012, 7, e34908. DOI: 10.1371/journal.pone.0039408

[37] Silva, G. M.; Netto, L. E. S.; Simoes, V.; SANTOS, L. F. A.; GOZZO, F. C.; Demasi, M. A. A.; Oliveira, C. L. P.; Bicev, R. N.; Klitzke, C. F.; Sogayar, M. C.; Demasi, M. Redox Control of 20S Proteasome Gating. Antioxidants & Redox Signaling 2012, 16, 1183-1194. DOI: 10.1089/ars.2011.4210

[36] Paiva, R. E. F.; Abbehausen, C.; GOMES, A. F.; GOZZO, F. C.; Lustri, W. R.; Formiga, A. L. B.; Corbi, P. P. Synthesis, spectroscopic characterization, DFT studies and antibacterial assays of a novel silver(I) complex with the anti-inflammatory nimesulide. Polyhedron 2012, 36, 112-119. DOI: 10.1016/j.poly.2012.02.002

[35] Fricker, L. D.; Gelman, J. S.; Castro, L. M.; GOZZO, F. C.; Ferro, E. S. Peptidomic Analysis of HEK293T Cells: Effect of the Proteasome Inhibitor Epoxomicin on Intracellular Peptides. Journal of Proteome Research 2012, 11, 1981-1990. DOI: 10.1021/pr2012076

[34] Nogueira, S. B.; Labate, C. A.; GOZZO, F. C.; PILAU, E. J.; Lajolo, F. M.; Nascimento, J. R. O. Proteomic analysis of papaya fruit ripening using 2DE-DIGE. Journal of Proteomics 2012, 75, 1428-1439. DOI: 10.1016/j.jprot.2011.11.015

[33] Santos, M. R.; GOMES, A. F.; GOZZO, F. C.; Suarez, P. A. Z.; Neto, B. A. D. Iron Complex with Ionic Tag-Catalyzed Olefin Reduction under Oxidative Conditions-A Different Reaction for Iron. ChemSusChem 2012, 5, 2383-2389. DOI: 10.1002/cssc.201200344

[32] Bergamini, F. R. G.; Ferreira, M. A.; Paiva, R. E. F.; GOMES, A. F.; GOZZO, F. C.; Formiga, A. L. B.; Corbi, F. C. A.; Mazali, I. O.; Alves, D. A.; Lancellotti, M.; Corbi, P. P. A binuclear silver complex with L-buthionine sulfoximine: synthesis, spectroscopic characterization, DFT studies and antibacterial assays. RSC Advances 2012, 2, 10372-10379. DOI: 10.1039/c2ra21433d

[31] Fasciotti, M.; GOMES, A. F.; GOZZO, F. C.; Iglesias, B. A.; Sa, G. F.; Daroda, R. J.; Toganoh, M.; Furuta, H.; Araki, K.; Eberlin, M. N. Corrole isomers: intrinsic gas-phase shapes via traveling wave ion mobility mass spectrometry and dissociation chemistries via tandem mass spectrometry. Organic & Biomolecular Chemistry 2012, 10, 8396-8402. DOI: 10.1039/c2ob26209f

[30] Carvalho, M. A.; Souza, B. C.; Paiva, R. E. F.; Bergamini, F. R. G.; GOMES, A. F.; GOZZO, F. C.; Lustri, W. R.; Formiga, A. L. B.; Rigatto, G.; Corbi, P. P. Synthesis, spectroscopic characterization, DFT studies, and initial antibacterial assays in vitro of a new palladium(II) complex with tryptophan. Journal of Coordination Chemistry 2012, 65, 1700-1711. DOI: 10.1080/00958972.2012.679660

[29] Santos, M. R.; Diniz, J. R.; Arouca, A. M.; GOMES, A. F.; GOZZO, F. C.; Tamborim, S. M.; Parize, A. L.; Suarez, P. A. Z.; Neto, B. A. D. Ionically Tagged Iron Complex-Catalyzed Epoxidation of Olefins in Imidazolium-Based Ionic Liquids. ChemSusChem 2012, 5, 716-726. DOI: 10.1002/cssc.201100453

[28] Santos, A. M.; Schechtman, D.; Cardoso, A.C.; Clemente, C. F. M. Z.; Silva, J. C.; FIORAMONTE, M.; Pereira, M.B. M.; Marin, T. M.; Oliveira, P. S. L.; Figueira, A. C. M.; Oliveira, S. H. P.; Torriani, I. L.; GOZZO, F. C.; Neto, J. X.; Franchini, K. G. FERM domain interaction with myosin negatively regulates FAK in cardiomyocyte hypertrophy. Nature Chemical Biology. 2012, 8, 102-110. DOI: 10.1038/nchembio.717


[27] Oliveira, V. M.; Jesus, R. S.; GOMES, A. F.; GOZZO, F. C.; Umpierre, A. P.; Suarez, P. A. Z.; Rubim, J. C.; Neto, B. A. D. Catalytic Aminolysis (Amide Formation) from Esters and Carboxylic Acids: Mechanism, Enhanced Ionic Liquid Effect, and its Origin. ChemCatChem. 2011, 3, 1911-1920. DOI: 10.1002/cctc.201100221

[26] SANTOS, L. F. A.; IGLESIAS, A. H.; GOZZO, F. C. Fragmentation features of intermolecular cross-linked peptides using N-hydroxy-succinimide esters by MALDI- and ESI-MS/MS for use in structural proteomics. Journal of Mass Spectrometry. 2011, 46, 742-750. DOI: 10.1002/jms.1951

[25] Rodriguez, M. A.; Cabrera, G.; GOZZO, F. C.; Eberlin, M. N.; Godeas, A. Clonostachys rosea BAFC3874 as a Sclerotinia sclerotiorum antagonist: mechanisms involved and potential as a biocontrol agent. Journal of Applied Microbiology. 2011, 110, 1177-1186. DOI: 10.1111/j.1365-2672.2011.04970.x

[24] SANTOS, L. F. A.; Eberlin, M. N.; GOZZO, F. C. IRMPD and ECD fragmentation of intermolecular cross-linked peptides. Journal of Mass Spectrometry. 2011, 46, 262-268. DOI: 10.1002/jms.1891

[23] Chiste, R. C.; Yamashita, F.; GOZZO, F. C.; Mercadante, A. Z. Simultaneous extraction and analysis by high performance liquid chromatography coupled to diode array and mass spectrometric detectors of bixin and phenolic compounds from annatto seeds. Journal of Chromatography A. 2011, 1218, 57-63. DOI: 10.1016/j.chroma.2010.10.094

[22] Castello, W. S.; Spera, M. B. M.; GOMES, A. F.; GOZZO, F. C.; Lustri, W. R.; Formiga, A. L. B.; Corbi, P. P. Synthesis, spectroscopic characterization, and antibacterial assays in vitro of a new platinum(II) complex with methionine sulfoxide. Journal of Coordination Chemistry. 2011, 64, 272-280. DOI: 10.1080/00958972.2010.540325

[21] Bergamini, F. R. G.; Abbehausen, C.; Magalhaes, A.; Lustri, W. R.; GOMES, A. F.; GOZZO, F. C.; Corbi, P. P. Synthesis, spectroscopic studies, and preliminary antibacterial assays of a palladium(II) complex with 2-mercaptothiazoline. Journal of Coordination Chemistry. 2011, 64, 3092 -3101. DOI: 10.1080/00958972.2011.613463

[20] Vessecchi, R.; Lopes, N. P.; GOZZO, F. C.; Doerr, F. A.; Murgu, M.; Lebre, D. T.; Abreu, R.; Bustillos, O. V.; Riveros, J. M. Mass Spectrometry Nomenclature in Portuguese Language. Química Nova. 2011, 34,1875-1887. DOI: 10.1590/S0100-40422011001000025 

[19] Pessoa, G. de S.; PILAU, E. J.; GOZZO, F. C.; Arruda, M. A. Z. Ion mobility mass spectrometry: an elegant alternative focusing on speciation studies. Journal of Analytical Atomic Spectrometry. 2011, 26,201-206. DOI: 10.1039/c0ja00139b


[18] Castro, L. M.; Berti, D. A.; Russo, L. C.; Coelho, V.; GOZZO, F. C.; Oliveira, V.; Ferro, E. S. Similar Intracellular Peptide Profile of TAP1/beta 2 Microglobulin Double-Knockout Mice and C57BL/6 Wild-Type Mice as Revealed by Peptidomic Analysis. The AAPS Journal. 2010, 12,608-616. DOI: 10.1208/s12248-010-9224-y  

[17] Gomes, I.; Dale, C. S.; Casten, K.; Geigner, M. A.; GOZZO, F. C.; Ferro, E. S.; Heimann, A. S.; Devi, L. A. Hemoglobin-derived Peptides as Novel Type of Bioactive Signaling Molecules. AAPS Journal. 2010, 12, 658-669. DOI: 10.1208/s12248-010-9217-x

[16] SANTOS, L. F. A.; IGLESIAS, A. H.; PILAU, E. J.; GOMES, A. F.; GOZZO, F. C. TI Traveling-Wave Ion Mobility Mass Spectrometry Analysis of Isomeric Modified Peptides Arising from Chemical Cross-Linking. Journal of the American Society for Mass Spectrometry. 2010, 21, 2062-2069. DOI: 10.1016/j.jasms.2010.08.017

[15] Soares, M. R.; Facincani, A. P.; Ferreira, R. M.; Moreira, L. M.; de Oliveira, J. C. F.; Ferro, J. A.; Ferro, M. I. T.; Meneghini, R.; GOZZO, F. C. Proteome of the phytopathogen Xanthomonas citri subsp citri: a global expression profile. Proteome Science. 2010, 8, 55. DOI: 10.1186/1477-5956-8-55

[14] Oliveira, F. F. D.; Santos, D. C. B. D.; Lapis, A. A. M.; Correa, J. R.; GOMES, A. F.; GOZZO, F. C.; Moreira, P. F., Jr.; de Oliveira, V. C.; Quina, F. H.; Neto, B. A. D.On the use of 2,1,3-benzothiadiazole derivatives as selective live cell fluorescence imaging probes. Bioorganic & Medicinal Chemistry Letters. 2010, 20, 6001-6007. DOI: 10.1016/j.bmcl.2010.08.073

[13] Medinas, D. B.; GOZZO, F. C.; SANTOS, L. F. A.; IGLESIAS, A. H.; Augusto, O. A ditryptophan cross-link is responsible for the covalent dimerization of human superoxide dismutase 1 during its bicarbonate-dependent peroxidase activity. Free Radical Biology and Medicine. 2010, 49, 1046-1053. DOI: 10.1016/j.freeradbiomed.2010.06.018

[12] GOMES, A. F.; GOZZO, F. C. Chemical cross-linking with a diazirine photoactivatable cross-linker investigated by MALDI- and ESI-MS/MS. Journal of Mass spectrometry. 2010, 45, 892-899. DOI: 10.1002/jms.1776

[11] Ferreira, C. R.; Saraiva, S. A.; Catharino, R. R.; Garcia, J. S.; GOZZO, F. C.; Sanvido, G. B.; Santos, L. F. A.; Lo Turco, E. G.; Pontes, J. H. F.; Basso, A. C.; Bertolla, R. P.; Sartori, R.; Guardieiro, M. M.; Perecin, F.; Meirelles, F. V.; Sangalli, J. R.; Eberlin, M. N. Single embryo and oocyte lipid fingerprinting by mass spectrometry. Journal of Lipid Research. 2010, 51,1218-1227. DOI: 10.1194/jlr.D001768

[10] Romao, W.; Franco, M. F.; IGLESIAS, A. H.; Sanvido, G. B.; Maretto, D. A.; GOZZO, F. C.; Poppi, R. J.; Eberlin, M. N.; De Paoli, M. A. Fingerprinting of bottle-grade poly(ethylene terephthalate) via matrix-assisted laser desorption/ionization mass spectrometry. Polymer Degradation and Stability. 2010, 95, 666-671. DOI: 10.1016/j.polymdegradstab.2009.11.046

[9] Silva, M. A. O.; Garcia, J. S.; Souza, G. H. M. F.; Eberlin, M. N.; GOZZO, F. C.; Arruda, M. A. Z. Evaluation of sample preparation protocols for proteomic analysis of sunflower leaves. Talanta. 2010, 90, 1545-1551. DOI: 10.1016/j.talanta.2009.06.016

[8] IGLESIAS, A. H.; SANTOS, L. F. A.; GOZZO, F. C. Identification of Cross-Linked Peptides by High-Resolution Precursor Ion Scan. Analytical Chemistry. 2010, 82, 909-916. DOI: 10.1021/ac902051q


[7] IGLESIAS, A. H.; SANTOS, L. F. A.; GOZZO, F. C. Collision-Induced Dissociation of Lys-Lys Intramolecular Cross-linked Peptides. J. Am. Soc. Mass Spectrom. 200920, 557-566. DOI: 10.1016/j.jasms.2008.11.009


[6] Alves, B. S. C.; Oyama, S. Jr.; GOZZO, F. C.; Sanches, M.; Guimaraes, B. G.; Zanchin, N. I. T. Characterization of the human ortholog of Mov34 reveals eight N-terminal residues important for MPN domain stability. Biochemical and Biophysical Research Communications. 2006, 347, 608-615. DOI: 10.1016/j.bbrc.2006.06.133

[5] Oliveira, M. A.; Guimaraes, B. G.; Cussiol, J. R. R.; Medrano, F. J.; GOZZO, F. C.; Netto, L. E. S. Structural insights into enzyme-substrate interaction and characterization of enzymatic intermediates of organic hydroperoxide resistance protein from Xylella fastidiosa. Journal of Molecular Biology. 2006, 359, 433-445. DOI: 10.1016/j.jmb.2006.03.054

[4] Carneiro, F. R. G.; Silva, T. C. L.; Alves, A. C.; Haline-Vaz, T.; GOZZO, F. C.; Zanchin, N. I. T. Spectroscopic characterization of the tumor antigen NY-REN-21 and identification of heterodimer formation with SCAND1. Biochemical and Biophysical Research Communications. 2006, 260-268. DOI: 10.1016/j.bbrc.2006.02.140

[3] Murai, M. J.; Carneiro, F. R. G.; GOZZO, F. C.; Ierardi, DF; Pertinhez, T. A.; Zanchin, N. I. T. Identification and characterization of a proteolysis-resistant fragment containing the PCI domain in the Arabidopsis thaliana INT6/eIF3e translation factor. Cell Biochemistry and Biophysics. 2006, 522-529. DOI: 10.1385/CBB:44:3:522


[2] Tonhosolo, R.; D'Alexandri, F. L.; Genta, F. A; Wunderlich, G.; GOZZO, F. C.; Eberlin, M. N.; Peres, V. J.; Kimura, E. A.; Katzin, A. M. Identification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparum. Biochemical Journal. 2005, 392,117-126. DOI: 10.1042/BJ20050441

[1] Heimann A.S.; Favarato, M. H.; GOZZO, F. C.; Rioli, V.; Carreno, F. R.; Eberlin, M. N.; Ferro, E. S.; Krege, J. H.; Krieger, J. E. ACE gene titration in mice uncovers a new mechanism for ACE on the control of body weight. Physiological Genomics. 2005, 20, 173-182. DOI: 10.1152/physiolgenomics.00145.2004







COPYRIGHT | © 2005 - 2013 Dalton Mass Spectrometry Laboratory | All rights reserved